Recombinant p63 抗体 (AA 1-200)
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北京 101111
Quick Overview for Recombinant p63 抗体 (AA 1-200) (ABIN7868785)
抗原
See all p63 (TP63) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-200
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原理
- Recombinant TP63 Antibody / Tumor protein 63
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纯化方法
- Protein A affinity
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免疫原
- A portion of amino acids 1-200 was used as the immunogen for the recombinant TP63 antibody.
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亚型
- IgG2a, kappa
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应用备注
- Optimal dilution of the recombinant TP63 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant TP63 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- p63 (TP63) (Tumor Protein P63 (TP63))
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别名
- TP63
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背景
- P63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.
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UniProt
- Q9H3D4
抗原
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