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Recombinant p63 抗体 (AA 1-200)

The 小鼠 单克隆 anti-p63 antibody is suitable to detect p63 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7868784
发货至: 中国
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Quick Overview for Recombinant p63 抗体 (AA 1-200) (ABIN7868784)

抗原

See all p63 (TP63) 抗体
p63 (TP63) (Tumor Protein P63 (TP63))

抗体类型

Recombinant Antibody

适用

  • 80
  • 26
  • 22
  • 4
  • 3
  • 2

宿主

  • 53
  • 31
  • 1
小鼠

克隆类型

  • 46
  • 39
单克隆

标记

  • 75
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This p63 antibody is un-conjugated

应用范围

  • 47
  • 40
  • 26
  • 16
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  • 13
  • 11
  • 6
  • 2
  • 1
  • 1
  • 1
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  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

RTP63-6941
  • 抗原表位

    • 10
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-200

    原理

    Recombinant TP63 Antibody / Tumor protein 63 (azide and preservative free)

    纯化方法

    Protein A affinity

    免疫原

    A portion of amino acids 1-200 was used as the immunogen for the recombinant TP63 antibody.

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal dilution of the recombinant TP63 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant TP63 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    p63 (TP63) (Tumor Protein P63 (TP63))

    别名

    TP63

    背景

    P63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.

    UniProt

    Q9H3D4
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