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JAK1 抗体 (pTyr1034, pTyr1035)

Cited in 3+ publications. This anti-JAK1 antibody is a 兔 多克隆 antibody detecting JAK1 in WB, ELISA, IHC (p) 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN743333
发货至: 中国
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北京 101111
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Quick Overview for JAK1 抗体 (pTyr1034, pTyr1035) (ABIN743333)

抗原

See all JAK1 抗体
JAK1 (Janus Kinase 1 (JAK1))

适用

  • 119
  • 87
  • 65
  • 2
  • 2
  • 2
  • 2
人, 小鼠

宿主

  • 98
  • 25
  • 1
  • 1

克隆类型

  • 77
  • 48
多克隆

标记

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  • 3
  • 3
  • 3
  • 3
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  • 2
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This JAK1 antibody is un-conjugated

应用范围

  • 94
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  • 11
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
  • 抗原表位

    • 25
    • 25
    • 8
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    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    pTyr1034, pTyr1035

    交叉反应

    人, 小鼠

    预测反应

    Rat,Cow,Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human Jak1 around the phosphorylation site of Tyr1034 + Tyr1035

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Huang, Zhou, Li, Ming, Li, Wu, Chen, Zhao: "In vivo and in vitro effects of microRNA-221 on hepatocellular carcinoma development and progression through the JAK-STAT3 signaling pathway by targeting SOCS3." in: Journal of cellular physiology, Vol. 234, Issue 4, pp. 3500-3514, (2019) (PubMed).

    Iriyama, Hatta, Takei: "Direct effect of dasatinib on signal transduction pathways associated with a rapid mobilization of cytotoxic lymphocytes." in: Cancer medicine, Vol. 5, Issue 11, pp. 3223-3234, (2016) (PubMed).

  • 抗原

    JAK1 (Janus Kinase 1 (JAK1))

    别名

    Jak1 +

    背景

    Synonyms: Tyrosine-protein kinase JAK1, Janus kinase 1, JAK-1, JAK1, JAK1A, JAK1B

    Background: Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.

    基因ID

    3716

    UniProt

    P23458

    途径

    JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
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