JAK1 抗体 (pTyr1022, pTyr1023)
(4 references)-
- 抗原 See all JAK1 抗体
- JAK1 (Janus Kinase 1 (JAK1))
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抗原表位
- pTyr1022, pTyr1023
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This JAK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Phospho-JAK1 (Tyr1022/Tyr1023) Antibody detects endogenous levels of JAK1 only when phosphorylated at Tyr1034/Tyr1035, which site historically referenced as Tyr1022/Tyr1023.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- 免疫原
- A synthesized peptide derived from human JAK1 around the phosphorylation site of Tyr1022/Tyr1023.
- 亚型
- IgG
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anti-Janus Kinase 1 (JAK1) (AA 120-380) antibody
JAK1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 1 (JAK1) antibodyJAK1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Janus Kinase 1 (JAK1) (pTyr1022) antibodyJAK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 1 (JAK1) (AA 960-1040) antibodyJAK1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Janus Kinase 1 (JAK1) (AA 1020-1024) antibodyJAK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 1 (JAK1) (AA 866-899), (C-Term) antibodyJAK1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB43812 unconjugated
anti-Janus Kinase 1 (JAK1) antibodyJAK1 适用: 人, 大鼠 WB, IP 宿主: 小鼠 Monoclonal 7B1-B6-G7 unconjugated
anti-Janus Kinase 1 (JAK1) (AA 172-204), (N-Term) antibodyJAK1 适用: 人 WB 宿主: 兔 Polyclonal RB43809 unconjugated
anti-Janus Kinase 1 (JAK1) antibodyJAK1 适用: 人, 小鼠, 大鼠 IHC (p) 宿主: 小鼠 Monoclonal 7G6 unconjugated
anti-Janus Kinase 1 (JAK1) (Ser639) antibodyJAK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:500, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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: "Single-cell-level protein analysis revealing the roles of autoantigen-reactive B lymphocytes in autoimmune disease and the murine model." in: eLife, Vol. 10, (2021) (PubMed).
: "Combination of gemcitabine and erlotinib inhibits recurrent pancreatic cancer growth in mice via the JAK-STAT pathway." in: Oncology reports, Vol. 39, Issue 3, pp. 1081-1089, (2018) (PubMed).
: "A novel fluorinated triazole derivative suppresses macrophage activation and alleviates experimental colitis via a Twist1-dependent pathway." in: Biochemical pharmacology, Vol. 155, pp. 275-287, (2018) (PubMed).
: "BCL2L10 inhibits growth and metastasis of hepatocellular carcinoma both in vitro and in vivo." in: Molecular carcinogenesis, Vol. 56, Issue 3, pp. 1137-1149, (2017) (PubMed).
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: "Single-cell-level protein analysis revealing the roles of autoantigen-reactive B lymphocytes in autoimmune disease and the murine model." in: eLife, Vol. 10, (2021) (PubMed).
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- 抗原
- JAK1 (Janus Kinase 1 (JAK1))
- 别名
- JAK1 (JAK1 产品)
- 别名
- JAK1A antibody, JAK1B antibody, JTK3 antibody, AA960307 antibody, C130039L05Rik antibody, wu:fb93e10 antibody, jak1 antibody, Janus kinase 1 antibody, tyrosine-protein kinase JAK1 antibody, JAK1 antibody, Jak1 antibody, jak1 antibody, LOC100286690 antibody
- 背景
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Description: Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway (PubMed:7615558). Kinase partner for the interleukin (IL)-2 receptor (PubMed:11909529).
Gene: JAK1
- 分子量
- 130kDa
- 基因ID
- 3716
- UniProt
- P23458
- 途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
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