IKK-alpha /IKK-beta 抗体 (pSer180, pSer181)
(2 references)Quick Overview for IKK-alpha /IKK-beta 抗体 (pSer180, pSer181) (ABIN743303)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer180, pSer181
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human IKK alpha/IKK beta around the phosphorylation site of Ser180/Ser181
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亚型
- IgG
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anti-IKK-alpha /IKK-beta (pSer180), (pSer181) antibody
适用: 小鼠, 人, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-IKK-alpha /IKK-beta (pSer176), (pSer180) antibody适用: 小鼠, 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-IKK-alpha /IKK-beta (AA 151-200), (pSer180) antibody适用: 小鼠, 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-IKK-alpha /IKK-beta (AA 151-250) antibody适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-IKK-alpha /IKK-beta (pSer180), (pSer181) antibody适用: 小鼠, 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-IKK-alpha /IKK-beta (pSer176), (pSer177) antibody适用: 小鼠, 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-IKK-alpha /IKK-beta (Lys6) antibody适用: 小鼠, 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-IKK-alpha /IKK-beta (AA 141-190) antibody适用: 小鼠, 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-IKK-alpha /IKK-beta (AA 155-184) antibody适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling." in: Environmental toxicology and pharmacology, Vol. 41, pp. 241-50, (2016) (PubMed).
: "Kaempferol alleviates insulin resistance via hepatic IKK/NF-?B signal in type 2 diabetic rats." in: International immunopharmacology, Vol. 28, Issue 1, pp. 744-50, (2015) (PubMed).
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: "Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling." in: Environmental toxicology and pharmacology, Vol. 41, pp. 241-50, (2016) (PubMed).
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- IKK-alpha /IKK-beta
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别名
- IKK alpha / beta / 181
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背景
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Synonyms: I Kappa B Kinase Alpha, IKKalpha, IKK alpha, IkappaB kinase, IkB kinase alpha subunit, IKBKA, IKK 1, IKK A, IKK a kinase, IKK1, IKKA, Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B Cells, Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit, NFKBIKA, Nuclear Factor Kappa B Inhibitor Kinase Alpha, Nuclear factor NF kappa B inhibitor kinase alpha, Nuclear factor NFkappaB inhibitor kinase alpha, Nuclear Factor Of Kappa Light Chain Gene Enhancer In B Cells Inhibitor, TCF16, CHUK1, Conserved Helix Loop Helix Ubiquitous Kinase, Conserved helix loop ubiquitous kinase, I Kappa B Kinase 1, IKKA_HUMAN.
Background: Nuclear factor kappa B (NFkB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NFkB mediates the expression of a great variety of genes in response to extracellular stimuli including IL1, TNF alpha, and bacterial product LPS. NFkB is associated with IkB proteins in the cell cytoplasm, which inhibit NFkB activity. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta). IKK alpha and IKK beta interact with each other and both are essential for NFkB activation. IKK alpha specifically phosphorylates IkBa. IKKa is expressed in variety of human tissues.
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基因ID
- 1147
抗原
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