Recombinant HBEGF 抗体 (PE)
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北京 101111
Quick Overview for Recombinant HBEGF 抗体 (PE) (ABIN7867302)
抗原
See all HBEGF 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PE-conjugated Anti-HBEGF antibody(DMC500), IgG1 Chimeric mAb
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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亚型
- IgG1
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应用备注
- Flow Cyt 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid PBS with 0.05 % Proclin300, 1 % BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2°C-8°C for 6 months
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有效期
- 6 months
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- HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
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别名
- HBEGF
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背景
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Synonyms: DTR, DTS, DTSF, HEGFL
Target Background: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor:EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.[UniProtKB:Swiss-Prot Function]
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UniProt
- Q99075
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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