AMACR 抗体
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北京 101111
Quick Overview for AMACR 抗体 (ABIN7865557)
抗原
See all AMACR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-p504s mouse monoclonal, IHC504, purified
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纯化方法
- affinity chromatography
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免疫原
- Recombinant Human p504s
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亚型
- IgG1
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应用备注
- Optional[ICC/IF_dilution]: 1:50-1:200 (microwave treatment recommended)
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Tris pH 7.3-7.7 with 1 % BSA and 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- store at 2 - 8 °C
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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别名
- p504s
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背景
- P504s, also known as α-Methylacyl Coenzyme A Racemase (AMACR), is an enzyme localized in the peroxisome and mitochondria that functions in β-oxidation of branched chain fatty acids, as well as bile synthesis. AMACR has been clinically indicated as a tissue biomarker for prostate cancer and colorectal cancer, as well as high-grade prostatic intraepithelial neoplasia, a precursor lesion of prostate cancer. p504s overexpression has also been detected in a number of other cancers including ovarian, breast, bladder, lung, and renal cell carcinomas, lymphoma, and melanoma.
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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