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Recombinant CEA 抗体

The 兔 单克隆 anti-CEA antibody (Clone MSVA-465R) (ABIN7865504) specifically detects CEA in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7865504
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Recombinant CEA 抗体 (ABIN7865504)

抗原

See all CEA 抗体
CEA (Carcinoembryonic Antigen Gene Family (CEA))

抗体类型

Recombinant Antibody

适用

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克隆类型

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单克隆

标记

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This CEA antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

MSVA-465R
  • Expression System

    HEK-293 Cells

    原理

    Recombinant Carcinoembryonic Antigen (CEA) / CD66 Antibody

    特异性

    This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70 % are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

    纯化方法

    Ab produced in HEK293 cell mammalian-based expression system.

    免疫原

    Recombinant full-length human CEA protein

    亚型

    IgG, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. ,Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    CEA (Carcinoembryonic Antigen Gene Family (CEA))

    别名

    Carcinoembryonic Antigen

    背景

    Carcinoembryonic Antigen-related Cell Adhesion Molecule 5, CEACAM5, CD66, Biliary Glycoprotein (BGP-1)

    Colon: An at least moderate cytoplasmic CEA staining should be seen in the vast majority of columnar epithelial cells.

    分子量

    80-200kDa

    基因ID

    1048, 709196

    UniProt

    P06731
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