Recombinant TIA1 抗体
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北京 101111
Quick Overview for Recombinant TIA1 抗体 (ABIN7863453)
抗原
See all TIA1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant TIA1 (T-Cell-Restricted Intracellular Antigen-1) Antibody
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特异性
- The T cell intracellular antigen 1 (TIA 1) is a 17 kDa cytoplasmic granule associated protein also designated as GMP 17, for granule membrane protein of 17 kDa. The GMP 17/TIA 1 Molecule is expressed in cells possessing cytolytic potential and could be involved in the signaling cascade of Fas (CD95) mediated apoptosis. Within hematopoietic cell lines, the TIA1/1352R monoclonal antibody reacts with about 90 % of CD16+, 50 60 % of CD8+, and less than 10 % of CD4+ normal peripheral blood lymphocytes. It reacts with almost all monocytes and granulocytes. This antibody also reacts with CD4+ activated T cell clones, activated NK cell clones, and Con activated thymocytes, but not with B lymphocytes or B cell lines. TIA1 antibody labels cytotoxic T cells and natural killer cells (NK cells). It is also expressed in T-cell lymphoma, large granular lymphocyte (LGL) leukemia and hairy cell leukemia. TIA1 expression in T-cell malignancies may help in differentiating LGL leukemia (high expression) from T-cell lymphocytosis and other T-cell diseases (low expression). TIA1 may also be used to label tumor-infiltrating lymphocytes in the study of immune response to malignancies.
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纯化方法
- 200ug/ml of Ab purified from rabbit anti-serum by Protein A.
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免疫原
- Human bone marrow malignant cells from a non B, non T acute leukemia
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亚型
- IgG, kappa
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anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) antibody
TIA1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (AA 1-215) antibodyTIA1 适用: 人 IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3A3B9 unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (AA 1-193) antibodyTIA1 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (AA 1-215) antibodyTIA1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2A10B12 unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) antibodyKD Validated TIA1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB2175 unconjugated Recombinant Antibody
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (Internal Region) antibodyVerified TIA1 适用: 人 WB, IHC, IF, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) antibodyTIA1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (AA 1-214) antibodyTIA1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (Internal Region) antibodyTIA1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (C-Term) antibodyTIA1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))
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别名
- TIA1
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背景
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Cytotoxic granule associated RNA binding protein 1, mTIA-1, Nucleolysin TIA1 isoform p40, p40-TIA-1, RNA binding protein TIA1, TIAL1, TIAR, WDM
Human tonsil, spleen and lymph node, Human Ovary
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分子量
- 40kDa
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基因ID
- 7072, 413123
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UniProt
- P31483
抗原
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