YY1 抗体
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北京 101111
Quick Overview for YY1 抗体 (ABIN7863950)
抗原
See all YY1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- YY1 (Transcription Factor) Antibody
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特异性
- The YY1 transcription factor, also known as NF-E1 (human) and Delta or UCRBP (mouse) is of interest due to its diverse effects on a wide variety of target genes. YY1 is broadly expressed in a wide range of cell types and contains four C-terminal zinc finger motifs of the Cys-Cys-His-His type and an unusual set of structural motifs at its N-terminal end. It binds to downstream elements in several vertebrate ribosomal protein genes, where it apparently acts positively to stimulate transcription and can act either negatively or positively in the context of the immunoglobulin k 3' enhancer and immunoglobulin heavy-chain 79oΩE1 site as well as the P5 promoter of the adenoassociated virus. It thus appears that YY1 is a bifunctional protein, capable of functioning as an activator in some transcriptional control elements and a repressor in others.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- His-tagged YY1 protein
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亚型
- IgG2, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- YY1 (YY1 Transcription Factor (YY1))
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别名
- YY1
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背景
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CF1, Delta transcription factor, INO80 complex subunit S, NF E1, NFE1, Transcriptional repressor protein YY1, UCR motif DNA binding protein, UCRBP, Yin and yang 1, Yin and Yang 1 protein, YY-1, YY1 transcription factor
Human kidney|tonsil or cervix carcinoma tissues
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分子量
- 40/68kDa
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基因ID
- 7528, 388927
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UniProt
- P25490
抗原
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