Fibronectin 1 抗体
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北京 101111
Quick Overview for Fibronectin 1 抗体 (ABIN7862847)
抗原
See all Fibronectin 1 (FN1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Fibronectin (Fibrin/Heparin-Binding Domain) Antibody
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特异性
- Fibronectins are disulfide-linked, dimeric glycoproteins of ~440 kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Epitope of this MAb is located in the 29 kDa N-terminal fibrin- and heparin-binding domain of fibronectin. It does not cross-react with MMP-2, MMP-9, or TIMP-2. Fibronectins are involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- High molecular weight proteins secreted by cultivated human fibroblasts
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亚型
- IgG2a, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Fibronectin 1 (FN1)
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别名
- Fibronectin Fibrin
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背景
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Cold insoluble globulin (CIG), FINC, FN1, FNZ, GFND, GFND2, LETS, Migration stimulating factor (MSF), Ugl-Y3
SW156 cells. Prostate or Kidney.
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分子量
- 220kDa (monomer), 440kDa (dimer)
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基因ID
- 2335, 203717
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UniProt
- P02751
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途径
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy
抗原
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