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Fibronectin 1 抗体

The 小鼠 单克隆 anti-Fibronectin 1 antibody (Clone 616) (ABIN7862847) specifically detects Fibronectin 1 in IHC, IF 和 FACS. The antibody is reactive with 人 和 Pig samples.
产品编号 ABIN7862847
发货至: 中国
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Quick Overview for Fibronectin 1 抗体 (ABIN7862847)

抗原

See all Fibronectin 1 (FN1) 抗体
Fibronectin 1 (FN1)

适用

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人, Pig

宿主

  • 82
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  • 1
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小鼠

克隆类型

  • 75
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单克隆

标记

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This Fibronectin 1 antibody is un-conjugated

应用范围

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  • 1
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Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

616
  • 原理

    Fibronectin (Fibrin/Heparin-Binding Domain) Antibody

    特异性

    Fibronectins are disulfide-linked, dimeric glycoproteins of ~440 kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Epitope of this MAb is located in the 29 kDa N-terminal fibrin- and heparin-binding domain of fibronectin. It does not cross-react with MMP-2, MMP-9, or TIMP-2. Fibronectins are involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    High molecular weight proteins secreted by cultivated human fibroblasts

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    Fibronectin 1 (FN1)

    别名

    Fibronectin Fibrin

    背景

    Cold insoluble globulin (CIG), FINC, FN1, FNZ, GFND, GFND2, LETS, Migration stimulating factor (MSF), Ugl-Y3

    SW156 cells. Prostate or Kidney.

    分子量

    220kDa (monomer), 440kDa (dimer)

    基因ID

    2335, 203717

    UniProt

    P02751

    途径

    Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy
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