Recombinant Calnexin 抗体 (N-Term)
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Quick Overview for Recombinant Calnexin 抗体 (N-Term) (ABIN7860803)
抗原
See all Calnexin (CANX) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-300, N-Term
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原理
- Recombinant Calnexin (Endoplasmic Reticulum Marker) Antibody
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特异性
- It recognizes a protein of 90 kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant N-terminal fragment of human Calnexin protein (around aa 1-300) (exact sequence is proprietary)
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亚型
- IgG, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Calnexin (CANX)
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别名
- Calnexin
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背景
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Calnexin, CANX, CNX, IP90, Major histocompatibility complex class I antigen-binding protein p88, P90
HeLa|MCF-7 or U2OS cells. Kidney or small intestine. Brain, Heart, Intestine, Kidney, Liver, Lung, Pancreas, Skin, Skeletal muscle and Stomach
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分子量
- 90kDa
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基因ID
- 821, 567968
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UniProt
- P27824
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途径
- MAPK Pathway, Thyroid Hormone Synthesis
抗原
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