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CD35 抗体 (AA 650-850)

The 小鼠 单克隆 anti-CD35 antibody (Clone CR1-9444) (ABIN7860562) specifically detects CD35. The antibody is reactive with 人 samples.
产品编号 ABIN7860562
发货至: 中国
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Quick Overview for CD35 抗体 (AA 650-850) (ABIN7860562)

抗原

See all CD35 (CR1) 抗体
CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

适用

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宿主

  • 138
  • 112
  • 8
小鼠

克隆类型

  • 217
  • 38
  • 3
单克隆

标记

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This CD35 antibody is un-conjugated

应用范围

请咨询

克隆位点

CR1-9444
  • 抗原表位

    • 44
    • 28
    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
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    AA 650-850

    原理

    CD35 / CR1 (Follicular Dendritic Cell Marker) Antibody

    特异性

    CD35, complement receptor 1, is a cell membrane-bound, monomeric glycoprotein on numerous cell types including erythrocytes, leukocytes, glomerular podocytes, and follicular dendritic cells. The primary function of CD35 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules.CD35 antigen is found on erythrocytes, B cells, a subset of T cells, monocytes, as well as eosinophils, and neutrophils. Anti-CD35 is considered a mature B-cell marker which labels follicular dendritic reticulum cells and tumors derived from such cells such as follicular dendritic cell tumor/sarcoma.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (within aa650-850) of human CD35 (exact sequence is proprietary)

    亚型

    IgG2b, kappa
  • 限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

    别名

    CD35

    背景

    C3 binding protein, C3b/C4b receptor, C3BR, C4BR, Complement Component (3b/4b) receptor 1 including Knops blood group system, Complement receptor type 1, KN, Knops blood group antigen

    Follicular dendritic cells (FDC) in tonsil.

    分子量

    224kDa

    基因ID

    1378, 334019

    UniProt

    P17927

    途径

    Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity
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