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CD35 抗体

CR1 适用: 人, Baboon, Cynomolgus, 猕猴 FACS, IHC, IF, StM 宿主: 小鼠 Monoclonal E11 unconjugated
产品编号 ABIN6939177
发货至: 中国
  • 抗原 See all CD35 (CR1) 抗体
    CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))
    适用
    • 100
    • 24
    • 22
    • 16
    • 16
    • 14
    • 14
    • 4
    • 3
    人, Baboon, Cynomolgus, 猕猴
    宿主
    • 65
    • 37
    • 2
    小鼠
    克隆类型
    • 73
    • 28
    • 3
    单克隆
    标记
    • 45
    • 11
    • 9
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD35 antibody is un-conjugated
    应用范围
    • 65
    • 37
    • 28
    • 25
    • 21
    • 20
    • 18
    • 16
    • 15
    • 13
    • 13
    • 11
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)
    特异性
    Recognizes a protein of 210-220 kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This MAb is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein.Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.
    纯化方法
    Purified by Protein A/G
    免疫原
    Intact human monocytes
    克隆位点
    E11
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CR1 Primary Antibody
  • 应用备注

    Positive Control: Follicular dendritic cells (FDC) in tonsil.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))
    别名
    CR1 (CR1 产品)
    别名
    C3BR antibody, C4BR antibody, CD35 antibody, KN antibody, C3DR antibody, CD21 antibody, Cr-1 antibody, Cr-2 antibody, Cr1 antibody, CR1-L antibody, CR2 antibody, CR1 antibody, complement C3b/C4b receptor 1 (Knops blood group) antibody, complement receptor 2 antibody, complement component (3d/Epstein Barr virus) receptor 2 antibody, complement receptor type 1 antibody, CR1 antibody, Cr2 antibody, CR2 antibody, LOC718120 antibody
    分子量
    210-220kDa
    基因ID
    1378
    UniProt
    P17927
    途径
    Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity
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