Recombinant CD31 抗体 (AA 538-738)
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Quick Overview for Recombinant CD31 抗体 (AA 538-738) (ABIN7860364)
抗原
See all CD31 (PECAM1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 538-738
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原理
- Recombinant CD31 / PECAM-1 (Endothelial Cell Marker) Antibody
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特异性
- CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa 538-738) of human PECAM1 protein (exact sequence is proprietary)
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亚型
- IgG, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
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别名
- CD31
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背景
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EndoCAM, PECA1, Platelet Endothelial Cell Adhesion Molecule 1, GPIIA'
Jurkat or THP-1 cells. Human tonsil or angiosarcoma.
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分子量
- ~100kDa (endothelium) and ~130kDa (platelets) 79oΩ
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基因ID
- 5175
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UniProt
- P16284
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途径
- Regulation of Actin Filament Polymerization
抗原
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