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Recombinant PAI1 抗体 (N-Term)

This 小鼠 单克隆 antibody specifically detects PAI1 in WB 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN7857716
发货至: 中国
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Quick Overview for Recombinant PAI1 抗体 (N-Term) (ABIN7857716)

抗原

See all PAI1 (SERPINE1) 抗体
PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

抗体类型

Recombinant Antibody

适用

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宿主

  • 131
  • 34
  • 8
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  • 1
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  • 1
小鼠

克隆类型

  • 126
  • 61
单克隆

标记

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This PAI1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

RTJA6
  • 抗原表位

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    N-Term

    Expression System

    CHO Cells

    原理

    Recombinant Plasminogen Activator Inhibitor (Type 1) / PAI-1 (Breast Cancer Prognostic Marker) Antibody

    特异性

    This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia.

    纯化方法

    200ug/ml of Ab produced in CHO cell mammalian-based expression system.

    免疫原

    Prokaryotic recombinant protein corresponding to a 250 amino acid portion of the N-terminus of the human PAI-1 molecule

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

    别名

    Plasminogen Activator Inhibitor

    背景

    endothelial plasminogen activator inhibitor serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 serpin E1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

    A-431 cells. Human placenta, lung or breast cancer.

    分子量

    50kDa

    基因ID

    5054

    UniProt

    P05121

    途径

    p53 Pathway, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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