Recombinant Cathepsin G 抗体 (N-Term)
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Quick Overview for Recombinant Cathepsin G 抗体 (N-Term) (ABIN7857710)
抗原
See all Cathepsin G (CTSG) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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Expression System
- CHO Cells
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原理
- Recombinant Cathepsin G (Neutrophil Marker) Antibody
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特异性
- Cathepsins are members of the papain family of cysteine proteases which are involved in a variety of physiological processes such as proenzyme activation, enzyme inactivation, antigen presentation, hormone maturation, tissue remodeling and bone matrix resorption. Cathepsin G is a 29 kD serine protease and is located in neutrophilic polymorphonuclear leukocytes which contain specialized azurophil granules together with two other serine proteases, elastase and protease 3. These three proteases may participate in the killing and digestion of engulfed pathogens and in connective tissue remodeling at sites of inflammation. Cathepsin G has also been found to be essential for the induction of human natural killer cell cytotoxicity.
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纯化方法
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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免疫原
- Prokaryotic recombinant protein corresponding to a 124 amino acid N-terminal region of the cathepsin G molecule
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Cathepsin G (CTSG)
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别名
- Cathepsin G
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背景
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CATG
THP-1 cells. Human bone marrow or lymphoid tissue.
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分子量
- 32kDa
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基因ID
- 1511
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UniProt
- P08311
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途径
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
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