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Recombinant ErbB2/Her2 抗体 (AA 1155-1255)

This 小鼠 单克隆 antibody specifically detects ErbB2/Her2 in IHC. It exhibits reactivity toward 人.
产品编号 ABIN7857629
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
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Quick Overview for Recombinant ErbB2/Her2 抗体 (AA 1155-1255) (ABIN7857629)

抗原

See all ErbB2/Her2 抗体
ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ErbB2/Her2 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

RERBB2-9401
  • 抗原表位

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    AA 1155-1255

    Expression System

    CHO Cells

    原理

    Recombinant HER-2 / c-erbB-2 / neu / CD340 Antibody

    特异性

    Recognizes a protein of 185 kDa, which is identified as c-erbB-2/HER-2/neu. Its epitope is localized in the extracellular domain. C-erbB-2/HER-2 is a member of the EGFR family. This MAb is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.

    纯化方法

    200ug/ml of Ab produced in CHO cell mammalian-based expression system.

    免疫原

    Recombinant fragment (around aa1155-1255) of human ERBB2 protein (exact sequence is proprietary)

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

    别名

    HER-2

    背景

    p185, CD340, Verb b2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog

    SKBR-3 cells. Human breast carcinoma tissue (IHC).

    分子量

    185kDa

    基因ID

    2064, 446352

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
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