ErbB2/Her2 抗体 (C-Term)
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Quick Overview for ErbB2/Her2 抗体 (C-Term) (ABIN7448962)
抗原
See all ErbB2/Her2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Rabbit anti-ErbB2 IHC Antibody, Affinity Purified
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预测反应
- Mouse,Rat,Dog,Horse,Rabbit,Pig,Golden hamster,Panda,Cat,Orangutan,Monkey,Gorilla,Chimpanzee,American black bear,White-tufted-ear marmoset,Small-eared galago,Naked mole rat,Chinese hamster,Crab-eating macaque,Thirteen-lined ground squirrel,Northern white-cheeked gibbon
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纯化方法
- Affinity Purified
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免疫原
- Between AA 1200 and C-term
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亚型
- IgG
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anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 23-372) antibody
ErbB2/Her2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (C-Term) antibodyErbB2/Her2 适用: 人, 小鼠, 大鼠, 犬, 猴, 马, Pig, 兔, Cow, Hamster, Avian, Cat, 小鸡, 驴, 山羊, 豚鼠, 绵羊 WB, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (pTyr1248) antibodyErbB2/Her2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (pTyr877) antibodyErbB2/Her2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (pTyr1112) antibodyErbB2/Her2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 22-121) antibodyErbB2/Her2 适用: 人 WB, IF, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 3B1 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 311-462) antibodyErbB2/Her2 适用: 人 IHC, IF, FACS 宿主: 小鼠 Monoclonal ERBB2-2452 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 311-462) antibodyErbB2/Her2 适用: 人 IHC 宿主: 小鼠 Monoclonal ERBB2-3078 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 1205-1255) antibodyErbB2/Her2 适用: 人, 小鼠 WB, IHC, FACS, IP, ICC 宿主: 兔 Monoclonal BLR241L unconjugated Recombinant Antibody
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 22-121) antibodyErbB2/Her2 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4E1 unconjugated
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应用备注
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IHC-IF: 1:50 - 1:500
IHC: 1:100 - 1:500
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限制
- 仅限研究用
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浓度
- 250 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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别名
- ErbB2
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背景
- Background: ErbB2 is a member of the receptor tyrosine kinase family of proteins. The four members of this family are ErbB1 (Epidermal growth factor receptor, EGFR/HER1), ErbB2 (HER2/Neu), ErbB3 (HER3), and ErbB4 (HER4). The ErbB receptor members are single-pass transmembrane proteins with an extracellular ligand-binding domain and a cytoplasmic tyrosine-kinase domain. The epidermal growth factor (EGF) and its related proteins serve as the ligands for the ErbB receptors. Upon binding, the receptors heterodimerize, autophosphorylate and make contact with adapter molecules to transmit cellular signals involved in cell proliferation, survival, and differentiation. The ErbB2 receptor is the only member that does not interact with a ligand, but instead functions as a heterodimeric partner to coordinate signals from other ligand bound ErbB receptors. Amplification and/or overexpression of ErbB2 have been reported in many cancers.
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基因ID
- 2064
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NCBI登录号
- NP_004439
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UniProt
- P04626
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
抗原
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