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Axin 抗体 (AA 761-862)

Name: Axin 抗体 (AA 761-862)
SKU: ABIN740295
Availability: OutOfStock

This anti-Axin antibody is a 兔多克隆 antibody detecting Axin in WB, ELISA, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人和小鼠.

Lane 1: mouse heart probed with Rabbit Anti-Axin1 Polyclonal Antibody, Unconjugated (ABIN740295) at 1:300 overnight at 4 °C. (Axin 抗体 (AA 761-862))

1 image

产品编号 ABIN740295

发货至: 中国

Datasheet as PDF

Quick Overview for Axin 抗体 (AA 761-862) (ABIN740295)

抗原

See all Axin (AXIN1) 抗体

Axin (AXIN1) (Axin 1 (AXIN1))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This Axin antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product AXIN1 Primary Antibody

抗原表位
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AA 761-862

交叉反应

人, 小鼠

预测反应

Rat,Dog,Cow,Sheep,Pig,Guinea Pig

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human Axin1

亚型

IgG
anti-Axin 1 (AXIN1) (AA 546-752) antibody
AXIN1 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4E9F1 unconjugated

anti-Axin 1 (AXIN1) (AA 618-827) antibody
AXIN1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Axin 1 (AXIN1) (AA 643-740) antibody
AXIN1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2B11 unconjugated

anti-Axin 1 (AXIN1) (AA 546-752) antibody
AXIN1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4F10G1 unconjugated

anti-Axin 1 (AXIN1) (AA 653-862) antibody
AXIN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Axin 1 (AXIN1) (AA 710-738) antibody
AXIN1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Axin 1 (AXIN1) (AA 418-707) antibody
AXIN1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Axin 1 (AXIN1) (AA 654-863) antibody
AXIN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Axin 1 (AXIN1) (C-Term) antibody
Verified AXIN1 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

anti-Axin 1 (AXIN1) (AA 8-62) antibody
AXIN1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
抗原

Axin (AXIN1) (Axin 1 (AXIN1))

别名

Axin1

背景

Synonyms: AXIN, PPP1R49, Axin-1, Axis inhibition protein 1, hAxin, AXIN1
Background: Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects, down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. In Wnt signaling, probably facilitates the phosphorylation of CTNNB1 and APC by GSK3B. Likely to function as a tumor suppressor. Facilitates the phosphorylation of TP53 by HIPK2 upon ultraviolet irradiation. Enhances TGF-beta signaling by recruiting the RNF111 E3 ubiquitin ligase and promoting the degradation of inhibitory SMAD7. Also component of the AXIN1-HIPK2-TP53 complex which controls cell growth, apoptosis and development.

基因ID

8312

UniProt

O15169

途径

WNT signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling