CD51 抗体
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北京 101111
Quick Overview for CD51 抗体 (ABIN7828788)
抗原
See all CD51 (ITGAV) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Purified Anti-Mouse CD51 Antibody[RMV-7]
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纯化方法
- >98%, Protein A/G purified
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纯度
- >98 %
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免疫原
- Recombinant MouseCD51 protein
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亚型
- IgG1, kappa
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应用备注
- FCM 2 μg/mL(0.5x106-1x106 cells)
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限制
- 仅限研究用
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浓度
- ≥ 1 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.05 % non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
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有效期
- 12 months
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- CD51 (ITGAV) (Integrin alpha V (ITGAV))
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别名
- CD51
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背景
- Integrin alpha-V;Integrin αV chain;Vitronectin Receptor;αV integrin;Itgav;vitronectin R;integrin &alpha-V-V,CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αv integrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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UniProt
- P43406
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途径
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
抗原
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