Recombinant PDK2 抗体
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北京 101111
Quick Overview for Recombinant PDK2 抗体 (ABIN7828509)
抗原
See all PDK2 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant PDK2 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human PDK2 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:1000-1:10000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
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别名
- PDK2
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背景
- PDK,PDHK,Pyruvate dehydrogenase kinase isoform,Pyruvate dehydrogenase lipoamide kinase isozyme,[Pyruvate dehydrogenase [lipoamide]] kinase isozyme,isozyme,PDK2,PDHK2,PDKII,[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2,isozyme 2,mitochondrial,Pyruvate dehydrogenase kinase,Pyruvate dehydrogenase kinase isoform 2,Pyruvate dehydrogenase lipoamide kinase isozyme 2,[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2 (PDK2) is a kinase that plays a key role in the regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. PDK2 Mediates cellular responses to insulin and plays an important role in maintaining normal blood glucose levels and in metabolic adaptation to nutrient availability. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 46 kDa
Observed MW: 46 kDa
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UniProt
- Q15119
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途径
- PI3K-Akt Signaling, RTK signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
抗原
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