Recombinant PYCARD 抗体
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北京 101111
Quick Overview for Recombinant PYCARD 抗体 (ABIN7828507)
抗原
See all PYCARD 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant TMS1/ASC Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human TMS1/ASC fragment
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亚型
- IgG, kappa
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anti-PYD and CARD Domain Containing (PYCARD) (AA 50-195) antibody
PYCARD 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) antibodyPYCARD 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (C-Term) antibodyVerified PYCARD 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) antibodyPYCARD 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 3E9 unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (AA 1-120) antibodyPYCARD 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 1C3D3 unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (Internal Region) antibodyVerified PYCARD 适用: 人, 小鼠, 大鼠 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (N-Term) antibodyPYCARD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (AA 1-149) antibodyPYCARD 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (AA 1-195) antibodyPYCARD 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (AA 1-195) antibodyPYCARD 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB 1:1000,IHC 1:100-1:500,IF 1:50
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- PYCARD (PYD and CARD Domain Containing (PYCARD))
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别名
- TMS1/ASC
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背景
- CARD,ASC / TMS,PYCARD,ASC,CARD5,TMS,TMS-1,TMS1,PYD and CARD domain containing,ASC / TMS1,Apoptosis associated speck like protein containing a CARD,Apoptosis-associated speck-like protein containing a CARD,CARD 5,Caspase recruitment domain containing protein 5,Caspase recruitment domain protein 5,Caspase recruitment domain-containing protein 5,hASC,MGC10332,PYD and CARD domain containing protein,PYD and CARD domain-containing protein,Target of methylation induced silencing 1,Target of methylation-induced silencing 1,TMS 1,Target of methylation-induced silencing (TMS1)/Apoptosis-associated speck-like protein containing a CARD (ASC), also referred to as PYCARD and CARD5, is a 22- kDa pro-apoptotic protein containing an N-terminal pyrin domain (PYD) and a C-terminal caspase recruitment domain (CARD). TheASC/TMS1gene was originally found to be aberrantly methylated and silenced in breast cancer cells, and has since been found to be silenced in a number of other cancers, including ovarian cancer, glioblastoma, melanoma, gastric cancer, lung cancer, and prostate cancer. Expression of ASC/TMS1 can be induced by pro-apoptotic/inflammatory stimuli. During apoptosis ASC/TMS1 is re-distributed from the cytosol to the mitochondria and associates with mitochondrial Bax to trigger cytochrome c release and subsequent apoptosis. ASC/TMS1 has also been found to be a critical component of inflammatory signaling where it associates with and activates caspase-1 in response to pro-inflammatory signals. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 22, 15 kDa
Observed MW: 22, 15 kDa
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UniProt
- Q9ULZ3
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途径
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome
抗原
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