Recombinant Phospholipase C gamma 1 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant Phospholipase C gamma 1 抗体 (ABIN7828460)
抗原
See all Phospholipase C gamma 1 (PLCG1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Recombinant PLCG1 Monoclonal Antibody
-
纯化方法
- Protein A purified
-
亚型
- IgG, kappa
-
-
anti-phospholipase C, gamma 1 (PLCG1) (AA 1192-1291) antibody
PLCG1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2A2 unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (AA 1091-1290) antibodyPLCG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (pTyr771) antibodyPLCG1 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (AA 1192-1291) antibodyPLCG1 适用: 人, 大鼠, 猴 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 3C2D11 unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (AA 1192-1291) antibodyPLCG1 适用: 人, 小鼠 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 3H1C10 unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (AA 39-181) antibodyPLCG1 适用: 人, 大鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2F3D11 unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (pTyr783) antibodyPLCG1 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (pTyr783) antibodyPLCG1 适用: 小鼠, 大鼠 WB, ELISA, IF (p), IHC (p), IF (cc), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (Tyr771) antibodyPLCG1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C, gamma 1 (PLCG1) antibodyKD Validated PLCG1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2080 unconjugated Recombinant Antibody
-
-
应用备注
- WB 1:1000
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
-
有效期
- 12 months
-
-
- Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
-
别名
- PLCG1
-
背景
- PLCG,phospholipase C gamma,NCKAP,PLCgamma,PLC,PLCG1,NCKAP3,PLC-II,PLC1,PLC148,PLCgamma1,phospholipase C gamma 1,NCKAP3,phospholipase C gamma 1,PLC1,PLC148,PLCgamma1,PLC-II,Phosphoinositide-specific phospholipase C (PLC) plays a significant role in transmembrane signaling.In response to extracellular stimuli, such as hormones, growth factors, and neurotransmitters, PLC hydrolyzes phosphatidylinositol 4,5-bisphosphate (PIP2) to generate two secondary messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). At least four families of PLCs have been identified: PLCβ, PLCγ, PLCδ, and PLCε. Phosphorylation is one of the key mechanisms that regulate the activity of PLC. PLCγ is activated by both receptor and non-receptor tyrosine kinases. PLCγ forms a complex with EGF and PDGF receptors, which leads to the phosphorylation of PLCγ at Tyr771, 783, and 1248. Phosphorylation by Syk at Tyr783 activates the enzymatic activity of PLCγ1. PLCγ2 is engaged in antigen dependent signaling in B cells and collagen-dependent signaling in platelets. Phosphorylation by Btk or Lck at Tyr753, 759, 1197, and 1217 is correlated with PLCγ2 activity. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
-
分子量
-
Calculated MW: 149 kDa
Observed MW: 150 kDa The actual band is not consistent with the expectation.
-
UniProt
- P19174
-
途径
- RTK signaling, WNT signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals, VEGF Signaling
抗原
-
