Recombinant MUC1 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant MUC1 抗体 (ABIN7828401)
抗原
See all MUC1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Recombinant MUC1 Monoclonal Antibody
-
纯化方法
- Protein A purified
-
免疫原
- Recombinant human MUC1 fragment
-
亚型
- IgG, kappa
-
-
-
-
应用备注
- WB 1:500-1:1000,IHC 1:200-1:1000
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
-
有效期
- 12 months
-
-
- MUC1 (Mucin 1 (MUC1))
-
别名
- MUC1
-
背景
- MAM,CA 15,MUC,ADMCKD,ADMCKD1,CA 15-3,CD227,EMA,H23AG,KL-6,MAM6,MCD,MCKD,MCKD1,MUC-1,MUC-1/SEC,MUC-1/X,MUC1/ZD,PEM,PEMT,PUM,MUC1,CA15-3,mucin-1,CA15 3,CA153,Episialin,Carcinoma associated mucin,MUC 1,MUC1 beta,MUC1 CT,MUC1 NT,Mucin 1,Peanut reactive urinary mucin,Polymorphic epithelial mucin,Tumor associated mucin,MUC1/CA15-3 C-terminal,EMA,mucin 1,Breast carcinoma-associated antigen DF3,Cancer antigen 15-3,Carcinoma-associated mucin,Krebs von den Lungen-6,Peanut-reactive urinary mucin,Tumor-associated epithelial membrane antigen,Tumor-associated mucin,The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
-
分子量
-
Calculated MW: 17 kDa
Observed MW: 24 kDa The actual band is not consistent with the expectation.
-
UniProt
- P15941
-
途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
-