Recombinant MAP2K5 抗体
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北京 101111
Quick Overview for Recombinant MAP2K5 抗体 (ABIN7828398)
抗原
See all MAP2K5 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant MEK5 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human MEK5 fragment
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亚型
- IgG, kappa
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anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 251-350) antibody
MAP2K5 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-448) antibodyMAP2K5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal M1-E6 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-120) antibodyMAP2K5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1B4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-190) antibodyMAP2K5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-120) antibodyMAP2K5 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 1E5 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-190) antibodyMAP2K5 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-190) antibodyMAP2K5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) antibodyMAP2K5 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 385-412), (C-Term) antibodyMAP2K5 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (pSer137) antibodyMAP2K5 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))
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别名
- MEK5
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背景
- MEK,MKK,MAP2K,MAPKK,PRKMK,MAP2K5,HsT17454,MAPKK5,MEK5,PRKMK5,MKK5,Dual specificity mitogen activated protein kinase kinase 5,Dual specificity mitogen-activated protein kinase kinase 5,EC 2.7.12.2,kinase 5,MAP kinase kinase 5,MAP kinase kinase MEK5b,MAPK/ERK kinase 5,MAPKK 5,MEK 5,mitogen-activated,mitogen-activated protein kinase kinase 5,MP2K5,Protein kinase,SAPKK5,SKK5,MEK5 is a dual specific kinase that specifically activates ERK5 involved in the regulation of diverse cellular processes, including cell growth, survival, and differentiation. The MEK5-ERK5 pathway is activated in numerous cancer types and plays a role in tumor growth and metastasis. Pharmacological targeting of the MEK5-ERK5 pathway has been investigated as a strategy for cancer treatment. MEK5 is activated by a variety of stimuli, including growth factors, cytokines, and oxidative stress. Activation of MEK5 is triggered by upstream kinases MEKK2 and MEKK3, leading to phosphorylation of MEK5 at Ser311 and Thr315, which subsequently leads to MEK5 dependent phosphorylation of EKR5 at Thr218 and Tyr220. Phosphorylation of ERK5 leads to nuclear translocation and regulation of several oncogenic transcription factors, including MEF2C, c-Fos, c-Myc, and Sap1. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 49, 50 kDa
Observed MW: 49, 50 kDa
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UniProt
- Q13163
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway
抗原
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