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Recombinant LIM Domain Kinase 1 抗体

The 兔 单克隆 anti-LIM Domain Kinase 1 antibody is suitable to detect LIM Domain Kinase 1 in samples from 人. It has been validated for WB.
产品编号 ABIN7828355
发货至: 中国
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Quick Overview for Recombinant LIM Domain Kinase 1 抗体 (ABIN7828355)

抗原

See all LIM Domain Kinase 1 (LIMK1) 抗体
LIM Domain Kinase 1 (LIMK1)

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

  • 106
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单克隆

标记

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This LIM Domain Kinase 1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

A762
  • 原理

    Recombinant LIMK1 Monoclonal Antibody

    纯化方法

    Protein A purified

    亚型

    IgG, kappa
  • 应用备注

    WB 1:2000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    LIM Domain Kinase 1 (LIMK1)

    别名

    LIMK1

    背景

    EC 2.7.1.,LIM domain kinase,LIMK1,LIMK,LIMK-1,EC 2.7.1.37,LIM domain containing protein kinase,LIM domain kinase 1,LIM kinase,LIM motif containing protein kinase,LIMK 1,LIM kinases (LIMK1 and LIMK2) are serine/threonine kinases that have two zinc finger motifs, known as LIM motifs, in their amino-terminal regulatory domains. LIM kinases are involved in actin cytoskeletal regulation downstream of Rho-family GTPases, PAKs, and ROCK. PAK1 and ROCK phosphorylate LIMK1 or LIMK2 at the conserved Thr508 or Thr505 residues in the activation loop, increasing LIMK activity. Activated LIM kinases inhibit the actin depolymerization activity of cofilin by phosphorylation at the amino-terminal Ser3 residue of cofilin. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 73 kDa

    Observed MW: 70 kDa The actual band is not consistent with the expectation.

    UniProt

    P53667

    途径

    Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events
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