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Recombinant HMGB2 抗体

The 兔 单克隆 anti-HMGB2 antibody (Clone A533) (ABIN7828260) specifically detects HMGB2 in WB, IHC, IF 和 IP. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7828260
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant HMGB2 抗体 (ABIN7828260)

抗原

See all HMGB2 抗体
HMGB2 (High Mobility Group Box 2 (HMGB2))

抗体类型

Recombinant Antibody

适用

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人, 小鼠, 大鼠

宿主

  • 59
  • 11

克隆类型

  • 37
  • 33
单克隆

标记

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This HMGB2 antibody is un-conjugated

应用范围

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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

A533
  • 原理

    Recombinant HMGB2 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human HMGB2 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:500-1:1000,IHC 1:50-1:100,IF 1:50,IP 1:25-1:50

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    HMGB2 (High Mobility Group Box 2 (HMGB2))

    别名

    HMGB2

    背景

    HMGB,High mobility group box,High mobility group (nonhistone chromosomal) protein,HMG B,HMG,HMGB2,HMG2,C80539,High mobility group (nonhistone chromosomal) protein 2,High mobility group box 2,High mobility group protein 2,High mobility group protein B2,HMG 2,HMG B2,HMG-2,HMGB2 belongs to a family of highly conserved proteins that contain HMG box domains. HMGB2 is widely expressed during embryonic development, but it is restricted to lymphoid organs and testis in adult animals. HMGB2 facilitate the binding of Hox proteins, Oct proteins, p53, Rel proteins, and steroid hormone receptor proteins to their target gene promoters. Furthermore, HMGB2 interacts with RAG1 to facilitate RAG complex binding to the recombinant signal sequence (RSS) and stimulate DNA-bending and subsequent VDJ cleavage at antigen receptor genes. In addition to their functions in the nucleus, HMGB proteins play a significant role in extracellular signaling associated with inflammation. HMGB2 is secreted by myeloid cells and promotes proliferation and migration of endothelial cells by binding to the receptor for advanced glycation end products (RAGE). Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 24 kDa

    Observed MW: 24 kDa

    UniProt

    P26583

    途径

    Cellular Response to Molecule of Bacterial Origin
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