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HMGB2 抗体 (N-Term)

HMGB2 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4886620
发货至: 中国
  • 抗原 See all HMGB2 抗体
    HMGB2 (High Mobility Group Box 2 (HMGB2))
    抗原表位
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 65-97, N-Term
    适用
    • 55
    • 29
    • 21
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 43
    • 12
    克隆类型
    • 43
    • 12
    多克隆
    标记
    • 37
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This HMGB2 antibody is un-conjugated
    应用范围
    • 36
    • 21
    • 15
    • 13
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for High mobility group protein B2(HMGB2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    KSDKARYDRE MKNYVPPKGD KKGKKKDPNA PKR
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for High mobility group protein B2(HMGB2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: high mobility group box 2
    Protein Name: High mobility group protein B2
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human HMGB2 (65-97aa KSDKARYDREMKNYVPPKGDKKGKKKDPNAPKR), identical to the related mouse and rat sequences.
    亚型
    IgG
    Top Product
    Discover our top product HMGB2 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    HMGB2 (High Mobility Group Box 2 (HMGB2))
    别名
    HMGB2 (HMGB2 产品)
    别名
    HMG2 antibody, C80539 antibody, HMG-2 antibody, Hmg2 antibody, HIGH MOBILITY GROUP BETA 1 antibody, HMG BETA 1 antibody, NFD02 antibody, NFD2 antibody, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP D 02 antibody, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP D 2 antibody, high mobility group B2 antibody, hmgb2 antibody, hmgb2l antibody, im:6909096 antibody, wu:fa20b02 antibody, zgc:101854 antibody, wu:fb22b10 antibody, wu:fc95d12 antibody, zgc:123215 antibody, high mobility group box 2 antibody, high mobility group box 2 S homeolog antibody, high mobility group B2 antibody, high mobility group box 2b antibody, high mobility group box 2a antibody, HMGB2 antibody, Hmgb2 antibody, hmgb2.S antibody, hmgb2b antibody, hmgb2a antibody
    背景
    High-mobility group protein B2, also known as high-mobility group protein 2 (HMG-2), is a protein that in humans is encoded by the HMGB2 gene. This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.

    Synonyms: C80539 | HMG2 | HMG-2 | HMG 2 | HMG B2 | HMGB2 | P26583
    基因ID
    3148
    UniProt
    P26583
    途径
    Cellular Response to Molecule of Bacterial Origin
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