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Recombinant Gelsolin 抗体

This 兔 单克隆 antibody specifically detects Gelsolin in WB, FACS 和 IF. It exhibits reactivity toward 人.
产品编号 ABIN7828222
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant Gelsolin 抗体 (ABIN7828222)

抗原

See all Gelsolin (GSN) 抗体
Gelsolin (GSN)

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This Gelsolin antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

A536
  • 原理

    Recombinant Gelsolin Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human Gelsolin fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:500-1:2000,IF 1:50,FCM 1:50-1:100

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    Gelsolin (GSN)

    别名

    Gelsolin

    背景

    DKFZp313L,GSN,ADF,AGEL,gelsolin,Actin depolymerizing factor,DKFZp313L0718,Brevin,GELS,Actin-depolymerizing factor,Actin-depolymerizing factor,ADF,AGEL,Brevin,GELS,GSN,Gelsolin shares structural and functional homology to villin and adseverin/scinderin. It plays an important role in actin filament assembly by capping and severing actin proteins in a Ca2+-dependent manner. Gelsolin is important for cellular events that require cytoskeletal remodeling. Accordingly, cells from gelsolin knockout mice exhibit motility defects, including a failure to ruffle in response to growth factor stimulation. In humans, defects in gelsolin have been linked to amyloidosis type 5 (AMYL5), a hereditary disease characterized by cranial neuropathy, which appears to result from gelsolin amyloid deposition. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 81 kDa

    Observed MW: 81 kDa

    UniProt

    P06396

    途径

    Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy
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