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Recombinant Cyclin D3 抗体

This 兔 单克隆 antibody specifically detects Cyclin D3 in WB 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN7828141
发货至: 中国
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Quick Overview for Recombinant Cyclin D3 抗体 (ABIN7828141)

抗原

See all Cyclin D3 (CCND3) 抗体
Cyclin D3 (CCND3)

抗体类型

Recombinant Antibody

适用

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宿主

  • 96
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克隆类型

  • 78
  • 33
单克隆

标记

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This Cyclin D3 antibody is un-conjugated

应用范围

  • 82
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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

A203
  • 原理

    Recombinant Cyclin D3 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human Cyclin D3 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:500-1:2000,IHC 1:50-1:100

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    Cyclin D3 (CCND3)

    别名

    Cyclin D3

    背景

    G1 S specific cyclin D,G1/S specific cyclin D,G1/S-specific cyclin-D,CyclinD,cyclin D,CCND3,cyclin D3,CCND 3,CyclinD3,D3 type cyclin,G1 S specific cyclin D3,G1/S specific cyclin D3,G1/S-specific cyclin-D3,Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 33 kDa

    Observed MW: 33 kDa

    UniProt

    P30281

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
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