Recombinant CSF1R 抗体
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北京 101111
Quick Overview for Recombinant CSF1R 抗体 (ABIN7828128)
抗原
See all CSF1R 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant CSF-1R Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human CSF-1R fragment
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亚型
- IgG, kappa
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应用备注
- IHC 1:500-1:2000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
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别名
- CSF-1R
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背景
- FIM,CSF1R,C-FMS,CD115,CSF-1R,CSFR,FIM2,FMS,HDLS,M-CSF-R,BANDDOS,CSF-1 receptor,CSF-1-R,Macrophage colony-stimulating factor 1 receptor,MCSF Receptor,Proto-oncogene c-Fms,M-CSFR,c-fms,CSF-1R,FMS,C FMS,CD 115,CD115 antigen,CFMS,Colony stimulating factor 1 receptor,Colony stimulating factor I receptor,CSF 1 R,CSF 1R,CSF1 R,EC 2.7.10.1,FIM 2,FMS proto oncogene,FMS protooncogene,formerly,Macrophage colony stimulating factor 1 receptor,Macrophage colony stimulating factor I receptor,McDonough feline sarcoma viral (v fms) oncogene homolog,M-CSF Receptor,MCSF Receptor,MCSFR,Oncogen FMS,V-FMS McDonough feline sarcoma viral oncogen homolog,Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development. Required for normal male and female fertility, and for normal development of milk ducts and acinar structures in the mammary gland during pregnancy. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration, and promotes cancer cell invasion. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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UniProt
- P07333
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途径
- RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
抗原
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