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CSF1R 抗体 (AA 344-497)

CSF1R 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6B9H2 unconjugated
产品编号 ABIN1724928
发货至: 中国
  • 抗原 See all CSF1R 抗体
    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
    抗原表位
    • 20
    • 20
    • 18
    • 16
    • 16
    • 15
    • 14
    • 11
    • 9
    • 8
    • 7
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    • 2
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    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 344-497
    适用
    • 191
    • 135
    • 97
    • 17
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 224
    • 20
    • 8
    • 3
    • 2
    小鼠
    克隆类型
    • 226
    • 30
    • 1
    单克隆
    标记
    • 92
    • 27
    • 15
    • 14
    • 13
    • 9
    • 9
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    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This CSF1R antibody is un-conjugated
    应用范围
    • 173
    • 105
    • 80
    • 66
    • 50
    • 26
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    • 20
    • 12
    • 6
    • 5
    • 4
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    • 1
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    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human CSF1R (AA: 344-497) expressed in E. coli.
    克隆位点
    6B9H2
    亚型
    IgG2b
    Top Product
    Discover our top product CSF1R Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Morandi, Barbetti, Riverso, Dello Sbarba, Rovida: "The colony-stimulating factor-1 (CSF-1) receptor sustains ERK1/2 activation and proliferation in breast cancer cell lines." in: PLoS ONE, Vol. 6, Issue 11, pp. e27450, (2011) (PubMed).

    Kitagawa, Gouda, Kirii, Sugiyama, Ishihama, Fujii, Narumi, Akita, Yokota: "Characterization of kinase inhibitors using different phosphorylation states of colony stimulating factor-1 receptor tyrosine kinase." in: Journal of biochemistry, Vol. 151, Issue 1, pp. 47-55, (2011) (PubMed).

  • 抗原
    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
    别名
    CSF1R (CSF1R 产品)
    别名
    AI323359 antibody, CD115 antibody, CSF-1R antibody, Csfmr antibody, Fim-2 antibody, Fms antibody, M-CSF-R antibody, M-CSFR antibody, C-FMS antibody, CSFR antibody, FIM2 antibody, FMS antibody, HDLS antibody, PDGFRB antibody, MGC89146 antibody, CSF-1-R antibody, c-fms antibody, mrfms antibody, CSF1 antibody, M-CSF antibody, csf1r antibody, fms antibody, panther antibody, colony stimulating factor 1 receptor antibody, macrophage colony-stimulating factor receptor antibody, colony stimulating factor 1 receptor, a antibody, Csf1r antibody, CSF1R antibody, m-csfr antibody, csf1r antibody, csf1ra antibody
    背景

    Description: The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. ,

    Aliases: FMS, CSFR, FIM2, HDLS, C-FMS, CD115, CSF-1R, M-CSF-R

    分子量
    108 kDa
    基因ID
    1436
    HGNC
    1436
    途径
    RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
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