Recombinant COBRA1 抗体
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北京 101111
Quick Overview for Recombinant COBRA1 抗体 (ABIN7828123)
抗原
See all COBRA1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant NELF-B Monoclonal Antibody
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纯化方法
- Protein A purified
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亚型
- IgG, kappa
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应用备注
- WB 1:10000-1:20000,IHC 1:100,FCM 1:100,IP 1:50-1:100
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- COBRA1 (Cofactor of BRCA1 (COBRA1))
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别名
- NELF-B
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背景
- KIAA,COBRA,NELFB,COBRA1,NELF-B,KIAA1182,NELF-B is an essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNApolymerase II. The NELF complex causes transcriptional pausing and is counteracted by the P-TEFb kinase complex. It may be able toinduce chromatin unfolding. NELF-B is a modulator of ligand dependent and independent expression of estrogen receptor-α target genes.NELF-B expression is reduced in metastatic and recurrent breast cancer, suggesting that low levels of NELF-B in breast cancers may serveas an indicator for poor prognosis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 66 kDa
Observed MW: 70 kDa The actual band is not consistent with the expectation.
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UniProt
- Q8WX92
抗原
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