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Recombinant COBRA1 抗体

This 兔 单克隆 antibody specifically detects COBRA1 in WB, IHC, IP 和 FACS. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN7828123
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant COBRA1 抗体 (ABIN7828123)

抗原

See all COBRA1 抗体
COBRA1 (Cofactor of BRCA1 (COBRA1))

抗体类型

Recombinant Antibody

适用

  • 47
  • 15
  • 7
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 41
  • 6

克隆类型

  • 41
  • 6
单克隆

标记

  • 24
  • 5
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This COBRA1 antibody is un-conjugated

应用范围

  • 36
  • 21
  • 11
  • 6
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS)

克隆位点

A786
  • 原理

    Recombinant NELF-B Monoclonal Antibody

    纯化方法

    Protein A purified

    亚型

    IgG, kappa
  • 应用备注

    WB 1:10000-1:20000,IHC 1:100,FCM 1:100,IP 1:50-1:100

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    COBRA1 (Cofactor of BRCA1 (COBRA1))

    别名

    NELF-B

    背景

    KIAA,COBRA,NELFB,COBRA1,NELF-B,KIAA1182,NELF-B is an essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNApolymerase II. The NELF complex causes transcriptional pausing and is counteracted by the P-TEFb kinase complex. It may be able toinduce chromatin unfolding. NELF-B is a modulator of ligand dependent and independent expression of estrogen receptor-α target genes.NELF-B expression is reduced in metastatic and recurrent breast cancer, suggesting that low levels of NELF-B in breast cancers may serveas an indicator for poor prognosis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 66 kDa

    Observed MW: 70 kDa The actual band is not consistent with the expectation.

    UniProt

    Q8WX92
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