Recombinant Claudin 1 抗体
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北京 101111
Quick Overview for Recombinant Claudin 1 抗体 (ABIN7828115)
抗原
See all Claudin 1 (CLDN1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant Claudin-1 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human Claudin-1 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:500-1:2000,IHC 1:200-1:1000,IP 1:50-1:100
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- Claudin 1 (CLDN1)
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别名
- Claudin-1
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背景
- UNQ,PRO,CLD,CLDN1,CLD1,ILVASC,SEMP1,claudin-1,Claudin1,CLD 1,CLDN 1,SEMP 1,Senescence associated epithelial membrane protein,Senescence associated epithelial membrane protein 1,Senescence-associated epithelial membrane protein,UNQ481,PRO944,claudin-1,CLD1,ILVASC,SEMP1,Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 22 kDa
Observed MW: 18 kDa The actual band is not consistent with the expectation.
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UniProt
- O95832
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途径
- Cell-Cell Junction Organization, Hepatitis C
抗原
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