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Recombinant Claudin 1 抗体

The 兔 单克隆 anti-Claudin 1 antibody is suitable to detect Claudin 1 in samples from 人. It has been validated for WB, IHC 和 IP.
产品编号 ABIN7828115
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant Claudin 1 抗体 (ABIN7828115)

抗原

See all Claudin 1 (CLDN1) 抗体
Claudin 1 (CLDN1)

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

  • 88
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单克隆

标记

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This Claudin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

克隆位点

A187
  • 原理

    Recombinant Claudin-1 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human Claudin-1 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:500-1:2000,IHC 1:200-1:1000,IP 1:50-1:100

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    Claudin 1 (CLDN1)

    别名

    Claudin-1

    背景

    UNQ,PRO,CLD,CLDN1,CLD1,ILVASC,SEMP1,claudin-1,Claudin1,CLD 1,CLDN 1,SEMP 1,Senescence associated epithelial membrane protein,Senescence associated epithelial membrane protein 1,Senescence-associated epithelial membrane protein,UNQ481,PRO944,claudin-1,CLD1,ILVASC,SEMP1,Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 22 kDa

    Observed MW: 18 kDa The actual band is not consistent with the expectation.

    UniProt

    O95832

    途径

    Cell-Cell Junction Organization, Hepatitis C
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