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Claudin 1 抗体 (Tyr210)

CLDN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7179992
发货至: 中国
  • 抗原 See all Claudin 1 (CLDN1) 抗体
    Claudin 1 (CLDN1)
    抗原表位
    • 16
    • 15
    • 7
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Tyr210
    适用
    • 85
    • 51
    • 51
    • 22
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 77
    • 9
    克隆类型
    • 78
    • 8
    多克隆
    标记
    • 47
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This Claudin 1 antibody is un-conjugated
    应用范围
    • 75
    • 36
    • 25
    • 24
    • 17
    • 16
    • 14
    • 13
    • 8
    • 6
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA
    交叉反应
    人, 小鼠
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized non-phosphopeptide derived from Human Claudin 1 around the phosphorylation site of tyrosine 210 (G-K-D-Y(p)-V).
    亚型
    IgG
    Top Product
    Discover our top product CLDN1 Primary Antibody
  • 应用备注
    WB:1:500-1:3000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Claudin 1 (CLDN1)
    别名
    CLDN1 (CLDN1 产品)
    别名
    CLD1 antibody, ILVASC antibody, SEMP1 antibody, AI596271 antibody, cldn19 antibody, claudin-1 antibody, cld1 antibody, ilvasc antibody, semp1 antibody, CLDN1 antibody, claudin 1 antibody, claudin 1 S homeolog antibody, CLDN1 antibody, Cldn1 antibody, cldn1 antibody, cldn1.S antibody
    背景

    Background: Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions (). CLDN1 acts as a coreceptor for HCV entry into hepatic cells.

    Swisshelm K.L., Gene 226:285-295(1999).
    Halford S., Cytogenet. Cell Genet. 88:217-217(2000).
    Kraemer F., Hum. Genet. 107:249-256(2000).

    Aliases: Claudin-1 antibody, Claudin1 antibody, CLD 1 antibody, CLD1 antibody, CLD1_HUMAN antibody, CLDN 1 antibody, Cldn1 antibody, ILVASC antibody, SEMP 1 antibody, SEMP1 antibody, Senescence associated epithelial membrane protein 1 antibody, Senescence associated epithelial membrane protein antibody, Senescence-associated epithelial membrane protein antibody

    UniProt
    O95832
    途径
    Cell-Cell Junction Organization, Hepatitis C
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