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Claudin 1 抗体 (AA 121-211)

CLDN1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN686407
发货至: 中国
  • 抗原 See all Claudin 1 (CLDN1) 抗体
    Claudin 1 (CLDN1)
    抗原表位
    • 15
    • 15
    • 7
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 121-211
    适用
    • 89
    • 50
    • 50
    • 22
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 81
    • 9
    克隆类型
    • 82
    • 8
    多克隆
    标记
    • 47
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This Claudin 1 antibody is un-conjugated
    应用范围
    • 79
    • 40
    • 29
    • 23
    • 16
    • 16
    • 13
    • 12
    • 8
    • 6
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from mouse Claudin 1
    亚型
    IgG
    Top Product
    Discover our top product CLDN1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Wang, Chen, Liang, Yan, Lin, Liu, Luo, Huang, Li, Liu, Tang: "Notch inhibition promotes fetal liver stem/progenitor cells differentiation into hepatocytes via the inhibition of HNF-1?." in: Cell and tissue research, Vol. 357, Issue 1, pp. 173-84, (2014) (PubMed).

  • 抗原
    Claudin 1 (CLDN1)
    别名
    Claudin 1 (CLDN1 产品)
    别名
    CLD1 antibody, ILVASC antibody, SEMP1 antibody, AI596271 antibody, cldn19 antibody, claudin-1 antibody, cld1 antibody, ilvasc antibody, semp1 antibody, CLDN1 antibody, claudin 1 antibody, claudin 1 S homeolog antibody, CLDN1 antibody, Cldn1 antibody, cldn1 antibody, cldn1.S antibody
    背景

    Synonyms: AI596271, Claudin-1, Cldn1

    Background: Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions.

    基因ID
    12737
    UniProt
    O88551
    途径
    Cell-Cell Junction Organization, Hepatitis C
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