Recombinant CD70 抗体
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北京 101111
Quick Overview for Recombinant CD70 抗体 (ABIN7828092)
抗原
See all CD70 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant CD70 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human CD70 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:500-1:1000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- CD70 (CD70 Molecule (CD70))
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别名
- CD70
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背景
- Tumor necrosis factor ligand superfamily member,TNFSF,CD70,CD27-L,CD27L,CD27LG,TNFSF7,TNLG8A,CD27 ligand,CD70 antigen,Tumor necrosis factor ligand superfamily member 7,Ki-24,CD27L,TNFSF7,CD 27L,CD 70,CD27 L,CD27 LG,CD70 Molecule,Ki 24 antigen,Ki24 antigen,member 7,sCD27 Ligand,soluble CD27 Ligand,Surface antigen CD70,TNFSF 7,Tumor necrosis factor (ligand) superfamily,CD70 is a type II transmembrane glycoprotein and a member of the tumor necrosis factor ligand superfamily (TNFSF), also known as CD27L and TNFSF7. It is normally expressed on medullary thymic epithelial cells. Its expression is induced on activated lymphoid cells (B cells, T cells, and NK cells) and dendritic cells. CD70 is a ligand for CD27, a co-stimulatory receptor that plays an important role in T cell activation and proliferation. CD70 overexpression has been reported in various tumors such as renal cell carcinoma, glioblastoma, and non-small cell lung carcinoma and it's being actively pursued as a therapeutic target. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 23 kDa
Observed MW: 27,54,81 kDa The actual band is not consistent with the expectation.
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UniProt
- P32970
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途径
- Cancer Immune Checkpoints
抗原
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