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Recombinant CD40 抗体

This 兔 单克隆 antibody specifically detects CD40 in WB 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN7828084
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant CD40 抗体 (ABIN7828084)

抗原

See all CD40 抗体
CD40

抗体类型

Recombinant Antibody

适用

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克隆类型

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单克隆

标记

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This CD40 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

A417
  • 原理

    Recombinant CD40 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human CD40 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:1000-1:5000,IHC 1:200-1:1000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    CD40

    别名

    CD40

    背景

    CDW,B-cell surface antigen CD,Tumor necrosis factor receptor superfamily member,TNFRSF,CD40,Bp50,CDW40,TNFRSF5,p50,Tumor necrosis factor receptor superfamily member 5,B-cell surface antigen CD40,CD40L receptor,TNFRSF5,AI326936,B cell associated molecule CD40,B cell surface antigen CD40,B cell-associated molecule,CD 40,CD40 (protein),CD40 antigen,CD40 antigen (TNF receptor superfamily member 5),CD40 Molecule,CD40 protein,CD40 type II isoform,GP39,HIGM1,IGM,IMD3,isoform CRA_a,member 5,MGC9013,Nerve growth factor receptor related B lymphocyte activation molecule,OTTHUMP00000031699,OTTHUMP00000031700,TBAM,T-BAM,TNF receptor superfamily member 5,TNR5,TRAP,Tumor necrosis factor receptor superfamily,Tumor necrosis factor receptor superfamily member 5 precursor,The CD40 antigen is a 44-48 kDa type I integral membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. This antigen is found on B cell lines, is strongly expressed by interdigitating cells (IDC), basal epithelial cells, and is also present on macrophages, some endothelial cells, and follicular dendritic cells. It is a well-known regulator of T cell immunity including in cancer. CD40-ligand, primarily expressed on activated T cells, interacts with CD40 on APCs resulting in a 'licensed' state. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 32 kDa

    Observed MW: 44-48 kDa The actual band is not consistent with the expectation.

    UniProt

    P25942

    途径

    NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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