Recombinant PRAS40 抗体
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北京 101111
Quick Overview for Recombinant PRAS40 抗体 (ABIN7828007)
抗原
See all PRAS40 (AKT1S1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant PRAS40 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human PRAS40 fragment
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亚型
- IgG, kappa
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anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (pThr246) antibody
KD Validated AKT1S1 适用: 人 WB, IF (p), FACS 宿主: 兔 Monoclonal 23GB3855 unconjugated Recombinant Antibody
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 92-276) antibodyAKT1S1 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 6H1C6 unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 152-276) antibodyAKT1S1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) antibodyKD Validated AKT1S1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB645 unconjugated Recombinant Antibody
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 92-276) antibodyAKT1S1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4A11G7 unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 52-101) antibodyAKT1S1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) antibodyKD Validated AKT1S1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB640 unconjugated Recombinant Antibody
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (pThr246) antibodyAKT1S1 适用: 人 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 132-256) antibodyAKT1S1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) antibodyAKT1S1 适用: 人 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
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应用备注
- WB 1:500-1:1000,IHC 1:50-1:200
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))
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别名
- PRAS40
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背景
- PRAS,AKT1 substrate,AKT1S,AKT1S1,Lobe,PRAS40,AKT1 substrate 1,PRAS40 is a proline-rich protein with a molecular weight of 40 kDa that acts as a substrate for the serine / threonine kinase Akt. PRAS40 also binds mTOR to transduce Akt signals to the mTOR complex. Inhibition of mTOR signaling stimulates PRAS40 binding to mTOR, which in turn inhibits mTOR activity. PRAS40 interacts with raptor in mTOR complex 1 (mTORC1) in insulin-deprived cells and inhibits the activation of the mTORC1 pathway mediated by the cell cycle protein Rheb. Phosphorylation of PRAS40 by Akt at Thr246 relieves PRAS40 inhibition of mTORC1. mTORC1 in turn phosphorylates PRAS40 at Ser183. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 27 kDa
Observed MW: 40 kDa The actual band is not consistent with the expectation.
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UniProt
- Q96B36
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Autophagy, BCR Signaling, Warburg Effect
抗原
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