Recombinant GRK2 抗体
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Quick Overview for Recombinant GRK2 抗体 (ABIN7828004)
抗原
See all GRK2 (ADRBK1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant GRK2 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human GRK2 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:1000-1:5000,IF 1:50
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
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别名
- GRK2
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背景
- GRK,Adrenergic beta receptor kinase,Beta adrenergic receptor kinase,Beta-adrenergic receptor kinase,G protein coupled receptor kinase,G-protein coupled receptor kinase,ARBK,ADRBK,GRK2,ADRBK1,BARK1,BETA-ARK1,Adrenergic beta receptor kinase 1,ARBK1,Beta adrenergic receptor kinase 1,Beta ARK 1,Beta ARK1,Beta-adrenergic receptor kinase 1,Beta-ARK-1,FLJ16718,G protein coupled receptor kinase 2,G-protein coupled receptor kinase 2,BARK,Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity. Inhibits relaxation of airway smooth muscle in response to blue light. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 80 kDa
Observed MW: 80 kDa
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UniProt
- P25098
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途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
抗原
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