RYK 抗体 (AA 66-607)
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Quick Overview for RYK 抗体 (AA 66-607) (ABIN7825780)
抗原
See all RYK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 66-607
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原理
- Anti-RYK Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-RYK Antibody catalog # A07225-1. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RYK recombinant protein (Position: L66-V607). Human RYK shares 97.2% amino acid (aa) sequence identity with mouse RYK.
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RYK (RYK Receptor-Like Tyrosine Kinase (RYK))
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别名
- RYK
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背景
- The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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分子量
- 75 kDa
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基因ID
- 6259
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UniProt
- P34925
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途径
- RTK signaling, WNT signaling, Regulation of Cell Size
抗原
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