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PABPN1 抗体 (Middle Region)

This anti-PABPN1 antibody is a 兔 多克隆 antibody detecting PABPN1 in WB, IF, IHC, IP, ICC 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7825700
发货至: 中国

Quick Overview for PABPN1 抗体 (Middle Region) (ABIN7825700)

抗原

See all PABPN1 抗体
PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))

适用

  • 39
  • 23
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 1
人, 小鼠, 大鼠

宿主

  • 39

克隆类型

  • 20
  • 19
多克隆

标记

  • 18
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PABPN1 antibody is un-conjugated

应用范围

  • 31
  • 15
  • 15
  • 14
  • 14
  • 12
  • 8
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • 抗原表位

    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Middle Region

    原理

    Anti-PABPN1 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-PABPN1 Antibody catalog # A02445-2. Tested in WB, IHC, IF, ICC, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human PABPN1. Human PABPN1 shares 100% amino acid (aa) sequence identity with mouse PABPN1.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
    Immunofluorescence, 5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Immunoprecipitation, 0.5-2 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))

    别名

    PABPN1

    背景

    This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.

    分子量

    50 kDa

    基因ID

    8106

    UniProt

    Q86U42
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