NLRP6 抗体 (AA 14-887)
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北京 101111
Quick Overview for NLRP6 抗体 (AA 14-887) (ABIN7825618)
抗原
See all NLRP6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 14-887
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原理
- Anti-NLRP6 Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-NLRP6 Antibody catalog # A03636-2. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NLRP6 recombinant protein (Position: R14-E887). Human NLRP6 shares 71.7% and 72.9% amino acid (aa) sequence identity with mouse and rat NLRP6, respectively.
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))
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别名
- NLRP6
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背景
- The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.
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分子量
- 105 kDa
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基因ID
- 171389
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UniProt
- P59044
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途径
- Inflammasome
抗原
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