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KPNB1 抗体 (AA 8-871)

This anti-KPNB1 antibody is a 兔 多克隆 antibody detecting KPNB1 in WB. Suitable for 斑马鱼.
产品编号 ABIN7825492
发货至: 中国

Quick Overview for KPNB1 抗体 (AA 8-871) (ABIN7825492)

抗原

See all KPNB1 抗体
KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

适用

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斑马鱼

宿主

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克隆类型

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多克隆

标记

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This KPNB1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 8-871

    原理

    Anti-Zebrafish Importin Beta/KPNB1 Antibody

    产品特性

    Anti-Zebrafish Importin Beta/KPNB1 Antibody catalog #AZA0A0R4IMZ8. Tested in WB applications. This antibody reacts with Zebrafish. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived zebrafish Importin Beta/KPNB1 recombinant protein (Position: E8-K871)

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Zebrafish

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

    别名

    KPNB1

    背景

    Importin subunit beta-1 is a protein that in humans is encoded by the KPNB1 gene. Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Two transcript variants encoding different isoforms have been found for this gene.

    UniProt

    A0A0R48

    途径

    Protein targeting to Nucleus
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