CSF1R 抗体 (AA 409-977)
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北京 101111
Quick Overview for CSF1R 抗体 (AA 409-977) (ABIN7825319)
抗原
See all CSF1R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 409-977
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原理
- Anti-Zebrafish M-CSFR/CSF1R Antibody
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产品特性
- Anti-Zebrafish M-CSFR/CSF1R Antibody catalog #AZQ9I8N6. Tested in IHC applications. This antibody reacts with Zebrafish.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived zebrafish M-CSFR/CSF1R recombinant protein (Position: D409-C977)
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亚型
- IgG
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应用备注
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Immunohistochemistry, 2-5 μg/mL, Zebrafish
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
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别名
- CSF1R
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背景
- CSF1R(Colony-Stimulating Factor 1 Receptor) also known as MCSFR, FMS, c-FMS, CD115, ONCOGENE FMS or CD115 ANTIGEN, encodes a tyrosine kinase growth factor receptor for colony-stimulating factor-1, the macrophage-and monocyte-specific growth factor. The gene is located on long arm of chromosome 5(5q32) on the Crick(minus) strand. The as-yet-unidentified°CSF1 Rpromoter/enhancer sequences may be confined to the nucleotides separating the 2 genes or could potentially lie within the PDGFR gene itself. The encoded protein is a single pass type I membrane protein and acts as the receptor for°Colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. The encoded protein is atyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Kondo et al.(2000) showed that the endogenous myelomonocytic cytokine receptors for GM-CSF and macrophage colony-stimulating factor(CSF1R) are expressed at low to moderate levels on the more primitive hematopoietic stem cells, are absent on common lymphoid progenitors, and are upregulated after myeloid lineage induction by IL2.
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UniProt
- Q9I8N6
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途径
- RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
抗原
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