C10orf2 抗体 (AA 39-635)
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Quick Overview for C10orf2 抗体 (AA 39-635) (ABIN7825314)
抗原
See all C10orf2 (C10ORF2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 39-635
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原理
- Anti-Twinkle/TWNK Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-Twinkle/TWNK Antibody catalog # A32117. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Twinkle/TWNK recombinant protein (Position: R39-K635). Human Twinkle/TWNK shares 87.8% amino acid (aa) sequence identity with mouse Twinkle/TWNK.
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))
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别名
- TWNK
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背景
- This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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分子量
- 70 kDa
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基因ID
- 56652
抗原
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