Notch1 抗体 (Extracellular, N-Term)
Quick Overview for Notch1 抗体 (Extracellular, N-Term) (ABIN7823623)
抗原
See all Notch1 (NOTCH1) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 20-216, Extracellular, N-Term
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原理
- Anti-Notch1 Antibody (BSA and Azide free)
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特异性
- No off-targets reported for Notch2 or Notch3
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交叉反应
- 大鼠
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产品特性
- Our Anti-Notch1 mouse monoclonal primary antibody is produced in-house from hybridoma clone N253/32. It detects mouse and rat Notch1, and is purified by protein a chromatography. It is great for use in WB, ICC, ELISA.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.
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纯度
- Purified mAbs are >90 % specific antibody.
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免疫原
- Fusion protein amino acids 20-216 (extracellular N-terminus, EGF-like domains 1-5) of mouse Notch1 (accession number Q01705) produced recombinantly in E. Coli
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS7.4, carrier free
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储存液
- Azide free
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注意事项
- For maximum recovery of product, centrifuge the vial prior to removing the cap.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C.
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有效期
- 12 months
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- Notch1 (NOTCH1) (Notch 1 (NOTCH1))
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别名
- Notch1
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背景
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Synonyms: Neurogenic locus notch homolog protein 1 (Notch 1) (Motch A) (mT14) (p300) [Cleaved into: Notch 1 extracellular truncation (NEXT), Notch 1 intracellular domain (NICD)]
Description Logic: Our Anti-Notch1 mouse monoclonal primary antibody is produced from hybridoma clone N253/32. It detects mouse and rat Notch1, and is purified by protein a chromatography. It is great for use in WB, ICC, ELISA.
Gene Name Alternatives: Notch1 Motch
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分子量
- >270 kDa, ~120 kDa and smaller fragments (due to proteolysis)
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UniProt
- Q01705
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途径
- Notch Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
抗原
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