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Integrin beta 3 抗体 (AA 27-120) (Biotin)

Name: Integrin beta 3 抗体 (AA 27-120) (Biotin)
SKU: ABIN739031
Availability: OutOfStock

This anti-Integrin beta 3 antibody is a 兔多克隆 antibody detecting Integrin beta 3 in WB, ELISA, IHC (fro) 和 IHC (p). Suitable for 人和小鼠.

产品编号 ABIN739031

发货至: 中国

Quick Overview for Integrin beta 3 抗体 (AA 27-120) (Biotin) (ABIN739031)

抗原

See all Integrin beta 3 (ITGB3) 抗体

Integrin beta 3 (ITGB3)

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This Integrin beta 3 antibody is conjugated to Biotin

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product ITGB3 Primary Antibody

抗原表位
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2

2

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1
AA 27-120

交叉反应

人, 小鼠

预测反应

Cow,Pig,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human Integrin beta 3

亚型

IgG
anti-Integrin beta 3 (ITGB3) (AA 27-120) antibody
ITGB3 适用: 人, 小鼠 WB, FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Integrin beta 3 (ITGB3) (AA 134-376) antibody
ITGB3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Integrin beta 3 (ITGB3) antibody
ITGB3 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated

anti-Integrin beta 3 (ITGB3) (AA 27-179) antibody
ITGB3 适用: 人 IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 3E8A6 unconjugated

anti-Integrin beta 3 (ITGB3) (AA 385-490) antibody
ITGB3 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ITGB3-2145 unconjugated

anti-Integrin beta 3 (ITGB3) antibody (FITC)
ITGB3 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal VIPL2 FITC

anti-Integrin beta 3 (ITGB3) antibody (PerCP)
ITGB3 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal VIPL2 PerCP

anti-Integrin beta 3 (ITGB3) (AA 610-718) antibody
ITGB3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Integrin beta 3 (ITGB3) (AA 734-760) antibody
ITGB3 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Integrin beta 3 (ITGB3) (AA 135-377) antibody
ITGB3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C for 12 months.

有效期

12 months
抗原

Integrin beta 3 (ITGB3)

别名

Integrin beta 3

背景

Synonyms: GT, CD61, GP3A, BDPLT2, GPIIIa, BDPLT16, Integrin beta-3, Platelet membrane glycoprotein IIIa, ITGB3
Background: Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

分子量

87kDa

基因ID

3690

UniProt

P05106

途径

Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex