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beta Catenin 抗体 (AA 661-781)

Name: beta Catenin 抗体 (AA 661-781)
SKU: ABIN738621
Availability: OutOfStock

This anti-beta Catenin antibody is a 兔多克隆 antibody detecting beta Catenin in WB, FACS, ELISA, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人, 小鼠, 大鼠, Pig 和斑马鱼. This Primary Antibody has been cited in 8+ publications.

Knockdown of BAMBI suppressed Wnt/β-catenin signaling. (beta Catenin 抗体 (AA 661-781))

Formalin-fixed and paraffin-embedded rat brain labeled with Anti-? (beta Catenin 抗体 (AA 661-781))

Formalin-fixed and paraffin-embedded rat skin labeled with Anti-? (beta Catenin 抗体 (AA 661-781))

15 images

(8 references)

产品编号 ABIN738621

发货至: 中国

Quick Overview for beta Catenin 抗体 (AA 661-781) (ABIN738621)

抗原

See all beta Catenin (CATNB) 抗体

beta Catenin (CATNB) (Catenin, beta (CATNB))

适用

人, 小鼠, 大鼠, Pig, 斑马鱼

宿主

兔

克隆类型

多克隆

标记

This beta Catenin antibody is un-conjugated

应用范围

Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product CATNB Primary Antibody

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AA 661-781

交叉反应

人, 小鼠, Pig, 大鼠, 斑马鱼

预测反应

Cow,Sheep,Chicken,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human Beta catenin

亚型

IgG
anti-Catenin, beta (CATNB) (pSer33), (pSer37) antibody
CATNB 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Catenin, beta (CATNB) (C-Term) antibody
CATNB 适用: 人, 小鼠, 大鼠, 小鸡, Cow, 犬, Pig, 兔, 绵羊, 猴, Hamster, Avian, Cat, 驴, 山羊, 豚鼠, 马 WB, IF 宿主: 山羊 Polyclonal unconjugated

anti-Catenin, beta (CATNB) (C-Term) antibody
CATNB 适用: 人, 斑马鱼 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Catenin, beta (CATNB) (pSer33), (pSer37), (pThr41) antibody
CATNB 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Catenin, beta (CATNB) (AA 439-675) antibody
CATNB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Catenin, beta (CATNB) (AA 439-675) antibody
CATNB 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C11 unconjugated

anti-Catenin, beta (CATNB) antibody
CATNB 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 4A3H3 unconjugated

anti-Catenin, beta (CATNB) antibody
CATNB 适用: 人, 小鼠, Hamster WB, IP, ICC, ICFC 宿主: 小鼠 Monoclonal EM-22 unconjugated

anti-Catenin, beta (CATNB) (AA 764-781) antibody
CATNB 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Catenin, beta (CATNB) antibody
CATNB 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 2E4 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Zhu, Shen, Xu, Chen, Huang: "Suppression of Wnt5a, but not Wnts, relieves chronic post-thoracotomy pain via anti-inflammatory modulation in rats." in: Biochemical and biophysical research communications, Vol. 493, Issue 1, pp. 474-480, (2017) (PubMed).

Yang, Liu, Miao, Yang, Fu, Dou, Cai, Zong, Tan, Chen, Wang: "Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier." in: Oncotarget, Vol. 7, Issue 39, pp. 63839-63855, (2016) (PubMed).

Zheng, Liu, Li, Tang, Zhang, Tang: "Lithium posttreatment confers neuroprotection through glycogen synthase kinase-3β inhibition in intracerebral hemorrhage rats." in: Journal of neurosurgery, pp. 1-9, (2016) (PubMed).

Qi, Li, Xu, Chang, Shu, Zhou: "Therapeutic role of human hepatocyte growth factor (HGF) in treating hair loss." in: PeerJ, Vol. 4, pp. e2624, (2016) (PubMed).

Zhang, Shi, Song, Sun, Yang, Li: "BAMBI Promotes C2C12 Myogenic Differentiation by Enhancing Wnt/?-Catenin Signaling." in: International journal of molecular sciences, Vol. 16, Issue 8, pp. 17734-45, (2015) (PubMed).

Lu, Duan, Zhang, Wu, Wang: "Expression of Wnt3a, Wnt10b, ?-catenin and DKK1 in periodontium during orthodontic tooth movement in rats." in: Acta odontologica Scandinavica, pp. 1-7, (2015) (PubMed).

Hu, Meng, Yu, Hu, Mao: "Ubiquitin E3 ligase MARCH7 promotes ovarian tumor growth." in: Oncotarget, Vol. 6, Issue 14, pp. 12174-87, (2015) (PubMed).

Lian, Duan, Wu, Li, Chen, Wang, Cai, Weng: "Expression and Clinical Significance of Von Hippel-Lindau Downstream Genes: Jade-1 and β-Catenin Related to Renal Cell Carcinoma." in: Urology, (2012) (PubMed).
抗原

beta Catenin (CATNB) (Catenin, beta (CATNB))

别名

Beta catenin

背景

Synonyms: CTNNB, MRD19, armadillo, Catenin beta-1, Beta-catenin, CTNNB1, OK/SW-cl.35, PRO2286
Background: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion. Acts as a negative regulator of centrosome cohesion. Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization. Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2. Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML.

基因ID

1499

UniProt

P35222

途径

Peptide Hormone Metabolism